Elizabeth (Liz) Mary Holmes, 71, of West Lafayette, passed away on Saturday, April 29, 2023, surrounded by her loved ones at home. She was born September 21, 1951, in Northbrook, IL to the late Walter and Mary (Mooney) Diesch. On June 21, 1980, she married Robert Michael Holmes in Thorntown, IN. Liz graduated from DePauw University in 1973 with a BA in mathematics, and after spending a few years in actuarial sciences, she applied and was accepted to the College of Veterinary Medicine at Purdue University. A practicing veterinarian in the Lafayette area from the time of her graduation (DVM class of 1983), she was the founder and owner of Petsburgh Pet Care in Lafayette, IN until her retirement in 2022. In addition to serving pets and their humans for 39 years, she and her veterinary staff also rescued, treated, and found homes for many stray dogs and cats over the years. Liz was an avid gardener with a profound love of the natural world and the creatures that inhabit it. She also loved traveling with her husband and daughters, as exploration fed her pursuit of lifelong learning. Surviving along with her husband are two daughters, Jessica Holmes (partner Aleksander Cholewa) and Katie Holmes (partner Jeremy Harris); a newly arrived grandson, Mario Aleksander; her older brother, Robert Diesch of New Richmond, WI; and beloved pets, Dr. Fauci (gregarious feline) and Margot (rambunctious canine). She is preceded in death by her parents, her older sister Barbara, and several cherished dogs and cats. Memorial contributions may be made to The Nature Conservancy (www.Nature.org) in Liz’s memory. Memorial services will be private.